Search on: COMPLEMENT C3-C5 CONVERTASES 
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Descriptor English:   Complement C3-C5 Convertases 
Descriptor Spanish:   Convertasas del Complemento C3-C5 
Descriptor Portuguese:   Convertases dos Complementos C3-C5 
Synonyms English:   C3 Convertase  
Tree Number:   D12.776.124.486.274.045.387
Definition English:   Serine proteases that cleave COMPLEMENT C3 into COMPLEMENT C3A and COMPLEMENT C3B, or cleave COMPLEMENT C5 into COMPLEMENT C5A and COMPLEMENT C5B. These include the different forms of C3/C5 convertases in the classical and the alternative pathways of COMPLEMENT ACTIVATION. Both cleavages take place at the C-terminal of an ARGININE residue. 
Pharmacological Action:   Immunologic Factors
 
History Note English:   2006 (1978) 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
drug effects deficiency
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology pharmacokinetics
poisoning radiation effects
supply & distribution secretion
standards toxicity
therapeutic use ultrastructure
urine  
Record Number:   50828 
Unique Identifier:   D050577 

Occurrence in VHL:
 

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